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Chemical Compound Review:

TMS acetylene ethynyl-trimethyl-silane

Synonyms: PubChem12912, AGN-PC-0D7CFA, ACMC-1BQA3, AG-D-21237, ANW-15420, ...

Khan, S.I. et al., Yue, D. et al.

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High impact information on Trimethylsilylacetylene

(Trimethylsilyl)acetylene also undergoes this coupling/cyclization process with I(2), NBS, and the sulfur and selenium electrophiles to afford the corresponding 2-(trimethylsilyl)benzo[b]thiophenes [1].
Synthesis was carried out from protected 5-iodo-2'-deoxyuridine and trimethylsilylacetylene by Sonogashira palladium-catalyzed cross coupling reaction followed by selective phosphorylation and finally boronation [2].

References

Synthesis of 2,3-disubstituted benzo[b]thiophenes via palladium-catalyzed coupling and electrophilic cyclization of terminal acetylenes. Yue, D., Larock, R.C. J. Org. Chem. (2002) [Pubmed]
Synthesis of 5-ethynyl-2'-deoxyuridine-5'-boranomono phosphate as a potential thymidylate synthase inhibitor. Khan, S.I., Dobrikov, M.I., Shaw, B.R. Nucleosides Nucleotides Nucleic Acids (2005) [Pubmed]

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