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Chemical Compound Review:

NSC-147 2-aminobenzenesulfonic acid

Synonyms: NSC147, ACMC-1BKFT, CCRIS 4575, CHEBI:1015, A86805_ALDRICH, ...

Mampel, J. et al., Junker, F. et al., Lombardini, J.B.

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Disease relevance of NSC147

2-Aminobenzenesulphonic acid (2AS) is degraded by Alcaligenes sp. strain O-1 via a previously detected but unidentified intermediate [1].

High impact information on NSC147

In addition, 2-aminobenzenesulfonic acid also stimulated phosphorylation [2].
Growth of Alcaligenes sp. strain O-1 with 2-aminobenzenesulfonate (ABS; orthanilate) as sole source of carbon and energy requires expression of the soluble, multicomponent 2-aminobenzenesulfonate 2,3-dioxygenase system (deaminating) (ABSDOS) which is plasmid-encoded [3].

References

Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid. Junker, F., Field, J.A., Bangerter, F., Ramsteiner, K., Kohler, H.P., Joannou, C.L., Mason, J.R., Leisinger, T., Cook, A.M. Biochem. J. (1994) [Pubmed]
Effects of taurine and taurine analogues on the phosphorylation of a 44 kDa protein present in a mitochondrial subfraction of the rat heart: partial characterization of the 44 kDa phosphoprotein. Lombardini, J.B. J. Mol. Cell. Cardiol. (1994) [Pubmed]
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1. Mampel, J., Ruff, J., Junker, F., Cook, A.M. Microbiology (Reading, Engl.) (1999) [Pubmed]

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