Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AG-J-24531 cyclopenta-1,3-diene; 1-(1-cyclopenta-2,4...

Synonyms: AC1L2WSG, LS-87206, CTK5I1051, CTK8D8688, AR-1J2475, ...

Vashisht Gopal, Y.N. et al., Leung, H.W. et al.

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Disease relevance of Acetoferrocene

The mechanism by which monkeys are less susceptible than rats to the toxicity of acetylferrocene is not clear [1].

High impact information on Acetoferrocene

The first derivative, acetyl-substituted ferrocene (monoacetylferrocene), showed a minor inhibition of topoisomerase II activity along with a consequent inhibition of cancer cell proliferation [2].

References

Toxicological evaluation of substituted dicyclopentadienyliron (ferrocene) compounds. Leung, H.W., Hallesy, D.W., Shott, L.D., Murray, F.J., Paustenbach, D.J. Toxicol. Lett. (1987) [Pubmed]
Topoisomerase II poisoning and antineoplastic action by DNA-nonbinding diacetyl and dicarboxaldoxime derivatives of ferrocene. Vashisht Gopal, Y.N., Jayaraju, D., Kondapi, A.K. Arch. Biochem. Biophys. (2000) [Pubmed]

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