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Chemical Compound Review

KST-1B2756     4-amino-1-[(2R,3R,4S,5R)-3,4- dihydroxy-5...

Synonyms: AC1L3YSX, AC1Q6BTW, AR-1B3357, NSC 133115, 28307-19-9, ...
 
 
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High impact information on CTD

 

Biological context of CTD

 

Associations of CTD with other chemical compounds

  • Analysis of the crystal structures for cytidine deaminase complexed with substrate analog 3-deazacytidine, transition-state analog zebularine 3,4-hydrate, and product uridine establishes significant changes in the magnitude of atomic-scale fluctuations along the (approximate) reaction coordinate of this enzyme [2].

References

  1. Cytidine deaminase complexed to 3-deazacytidine: a "valence buffer" in zinc enzyme catalysis. Xiang, S., Short, S.A., Wolfenden, R., Carter, C.W. Biochemistry (1996) [Pubmed]
  2. Enzymatic conformational fluctuations along the reaction coordinate of cytidine deaminase. Noonan, R.C., Carter CW, C.W., Bagdassarian, C.K. Protein Sci. (2002) [Pubmed]
 
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