Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Sapropterin 2-amino-6-[(1R,2S)-1,2- dihydroxypropyl]-5...

Synonyms: SureCN4217501, CHEBI:64491, HMDB00787, AC1Q6INE, 6R-BH4, ...

Matei, V. et al.

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Disease relevance of AC1Q6INE

The present study shows that tetrahydrobiopterin markedly reduces portal hypertension and improves systemic hemodynamics in cirrhotic rats [1].

References

Three-day tetrahydrobiopterin therapy increases in vivo hepatic NOS activity and reduces portal pressure in CCl4 cirrhotic rats. Matei, V., Rodríguez-Vilarrupla, A., Deulofeu, R., García-Calderó, H., Fernández, M., Bosch, J., Garcia-Pagán, J.C. J. Hepatol. (2008) [Pubmed]

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