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SAE1  -  SUMO1 activating enzyme subunit 1

Homo sapiens

Synonyms: AOS1, FLJ3091, HSPC140, SUA1, SUMO-activating enzyme subunit 1, ...
 
 
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High impact information on SAE1

  • We report here that the adenoviral protein Gam1 inhibits the SUMO pathway by interfering with the activity of E1 (SAE1/SAE2) [1].
  • Here we report the identification of the sentrin-activating enzyme complex, which consists of two proteins AOS1 and UBA2 [2].
 

Analytical, diagnostic and therapeutic context of SAE1

References

  1. A mechanism for inhibiting the SUMO pathway. Boggio, R., Colombo, R., Hay, R.T., Draetta, G.F., Chiocca, S. Mol. Cell (2004) [Pubmed]
  2. Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex. Gong, L., Li, B., Millas, S., Yeh, E.T. FEBS Lett. (1999) [Pubmed]
 
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