The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

ARPC4  -  actin related protein 2/3 complex, subunit...

Homo sapiens

Synonyms: ARC20, Actin-related protein 2/3 complex subunit 4, Arp2/3 complex 20 kDa subunit, P20-ARC, p20-ARC, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on ARPC4

  • Subunits ARPC2 p34 and ARPC4 p20 in the core of the complex associate through long carboxyl-terminal alpha helices and have similarly folded amino-terminal alpha/beta domains [1].
  • The ARC20 was achieved by 22 (73%) of etanercept-treated patients compared with four (13%) of placebo-treated patients [2].
  • In contrast, p41-Arc only interacted with p20-Arc/p16-Arc heterodimer [3].
  • Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub [3].

References

  1. Crystal structure of Arp2/3 complex. Robinson, R.C., Turbedsky, K., Kaiser, D.A., Marchand, J.B., Higgs, H.N., Choe, S., Pollard, T.D. Science (2001) [Pubmed]
  2. Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Mease, P.J., Goffe, B.S., Metz, J., VanderStoep, A., Finck, B., Burge, D.J. Lancet (2000) [Pubmed]
  3. Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub. Zhao, X., Yang, Z., Qian, M., Zhu, X. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities