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Gene Review:

pepQ - proline dipeptidase

Escherichia coli CFT073

Stucky, K. et al.

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Disease relevance of pepQ

The gene designated pepR1, encoding a potential transcription regulator of Lactobacillus delbrueckii subsp. lactis DSM7290, was identified by sequence similarity of an open reading frame located upstream of the prolidase pepQ orientated in opposite direction. pepQ and pepR1 coding regions are spaced by 152 nucleotides [1].

High impact information on pepQ

The pepQ-beta-galactosidase hybrid displayed an enhanced expression in the presence of cloned pepR1 [1].

References

Characterization of pepR1, a gene coding for a potential transcriptional regulator of Lactobacillus delbrueckii subsp. lactis DSM7290. Stucky, K., Schick, J., Klein, J.R., Henrich, B., Plapp, R. FEMS Microbiol. Lett. (1996) [Pubmed]

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