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TIMM17A  -  translocase of inner mitochondrial...

Homo sapiens

Synonyms: Inner membrane preprotein translocase Tim17a, MIMT17, Mitochondrial import inner membrane translocase subunit Tim17-A, TIM17, TIM17A, ...
 
 
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High impact information on TIMM17A

  • Tim17p Regulates the Twin Pore Structure and Voltage Gating of the Mitochondrial Protein Import Complex TIM23 [1].
  • Further analysis of Tim17p mutants indicates that the N terminus is vital for both voltage sensing and protein sorting [1].
 

Other interactions of TIMM17A

  • These results suggest that although Tim23p is the main structural unit of the pore Tim17p is required for twin pore structure and provides the voltage gate for the TIM23 channel [1].

References

  1. Tim17p Regulates the Twin Pore Structure and Voltage Gating of the Mitochondrial Protein Import Complex TIM23. Martinez-Caballero, S., Grigoriev, S.M., Herrmann, J.M., Campo, M.L., Kinnally, K.W. J. Biol. Chem. (2007) [Pubmed]
 
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