The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

TM9SF1  -  transmembrane 9 superfamily member 1

Homo sapiens

Synonyms: HMP70, MP70, MP70 protein family member, Transmembrane 9 superfamily member 1, hMP70
 
 
 

High impact information on TM9SF1

 

  • Large N-terminal variable domain and nine putative transmembrane domains [1]
  • Gene expression of TM9SF1 appears to be ubiquitous, as the mRNA is detectable in all human tissues analysed so far, as shown by Northern blot analysis [1].
  • Member of the highly conserved TM9SF or nonaspanin family [1] [2] .
  • TM9SF1 induces autophagy [3].
  • The gene name MP70(hMP70) is not used anymore as it may be confounded with MP70(Cx50; connexin 50).

 

 

 

 

 

 

 

References

  1. Cloning of a human multispanning membrane protein cDNA: evidence for a new protein family. Chluba-de Tapia, J., de Tapia, M., Jäggin, V., Eberle, A.N. Gene (1997) [Pubmed]
  2. Comparative analysis of nonaspanin protein sequences and expression studies in zebrafish. Pruvot, B., Laurens, V., Salvadori, F., Solary, E., Pichon, L., Chluba, J. Immunogenetics. (2010) [Pubmed]
  3. High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene. He, P., Peng, Z., Luo, Y., Wang, L., Yu, P., Deng, W., An, Y., Shi, T., Ma, D. Autophagy. (2009) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities