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Gene Review

Air1  -  activator of immune response gene Ir1

Mus musculus

 
 
 
 
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High impact information on Air1

  • Physiologic target of the Air-1 trans-activator revealed by stable transfection assay [1].
  • H4 contains a single mouse chromosome, autosome 16, in which the Air-1 locus maps, and an entire RJ 2.2.5-derived genome [1].
  • In the present study we show that the physiologic target of the Air-1 locus product is contained within a limited HLA-DRA promoter sequence of 300 base pairs, encompassing the crucial Y, X, and W cis-acting elements [1].

References

  1. Physiologic target of the Air-1 trans-activator revealed by stable transfection assay. Sartoris, S., De Lerma Barbaro, A., Cestari, T., Tridente, G., Accolla, R.S. Immunogenetics (1994) [Pubmed]
 
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