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Gene Review

ACTL7A  -  actin-like 7A

Homo sapiens

Synonyms: Actin-like protein 7A, Actin-like-7-alpha
 
 
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Disease relevance of ACTL7A

 

High impact information on ACTL7A

  • ACTL7A encodes a 435-amino-acid protein (predicted molecular mass 48.6 kDa) and ACTL7B encodes a 415-amino-acid protein (predicted molecular mass 45. 2 kDa) that show greater than 65% amino acid identity to each other [1].
 

Anatomical context of ACTL7A

  • ACTL7A is expressed in a wide variety of adult tissues, while the ACTL7B message was detected only in the testis and, to a lesser extent, in the prostate [1].

References

  1. Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31. Chadwick, B.P., Mull, J., Helbling, L.A., Gill, S., Leyne, M., Robbins, C.M., Pinkett, H.W., Makalowska, I., Maayan, C., Blumenfeld, A., Axelrod, F.B., Brownstein, M., Gusella, J.F., Slaugenhaupt, S.A. Genomics (1999) [Pubmed]
 
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