The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

ACTL7B  -  actin-like 7B

Homo sapiens

Synonyms: Actin-like protein 7B, Actin-like-7-beta, Tact1
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of ACTL7B

 

High impact information on ACTL7B

  • This 8-cM (6-Mb) region is flanked by markers D9S172 and D9S105, and further candidate gene sequencing studies excluded the coding regions of three genes (ACTL7A, ACTL7B, and CTNNAL1) [2].
  • ACTL7A encodes a 435-amino-acid protein (predicted molecular mass 48.6 kDa) and ACTL7B encodes a 415-amino-acid protein (predicted molecular mass 45. 2 kDa) that show greater than 65% amino acid identity to each other [1].
 

Anatomical context of ACTL7B

  • ACTL7A is expressed in a wide variety of adult tissues, while the ACTL7B message was detected only in the testis and, to a lesser extent, in the prostate [1].

References

  1. Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31. Chadwick, B.P., Mull, J., Helbling, L.A., Gill, S., Leyne, M., Robbins, C.M., Pinkett, H.W., Makalowska, I., Maayan, C., Blumenfeld, A., Axelrod, F.B., Brownstein, M., Gusella, J.F., Slaugenhaupt, S.A. Genomics (1999) [Pubmed]
  2. African American hypertensive nephropathy maps to a new locus on chromosome 9q31-q32. Chung, K.W., Ferrell, R.E., Ellis, D., Barmada, M., Moritz, M., Finegold, D.N., Jaffe, R., Vats, A. Am. J. Hum. Genet. (2003) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities