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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

LILRA1  -  leukocyte immunoglobulin-like receptor,...

Homo sapiens

Synonyms: CD85 antigen-like family member I, CD85I, CD85i, LIR-6, LIR6, ...
 
 
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High impact information on LILRA1

  • A free H chain form of HLA-B27 bound ILT4 and LIR6 [1].
  • The 3' untranslated region of the gene for LIR-6 contains a 37-base pair repeat not present in the LIR-1 or LIR-5 genes [2].
  • We describe the organization and fine localization of the genes for LIR-1 and LIR-5, which are inhibitory receptors, and LIR-6, which is an activating receptor [2].

References

  1. Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures. Allen, R.L., Raine, T., Haude, A., Trowsdale, J., Wilson, M.J. J. Immunol. (2001) [Pubmed]
  2. Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4. Liu, W.R., Kim, J., Nwankwo, C., Ashworth, L.K., Arm, J.P. Immunogenetics (2000) [Pubmed]
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