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Gene Review

DYX3  -  dyslexia susceptibility 3

Homo sapiens

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Psychiatry related information on DYX3


High impact information on DYX3

  • The isolation and molecular characterisation of this newly reported gene on chromosome 2 (DYX3) and DYX1 will thus provide new and exciting insights into the processes involved in reading and spelling [1].
  • The dyslexia candidate region on 2p11 is, therefore, now limited to the chromosomal area D2S2116-D2S2181, which is approximately 12 Mbp of human sequence and is at a distinct location from the previously reported DYX3 locus, raising the possibility of two distinct loci on chromosome 2p [2].


  1. A new gene (DYX3) for dyslexia is located on chromosome 2. Fagerheim, T., Raeymaekers, P., Tønnessen, F.E., Pedersen, M., Tranebjaerg, L., Lubs, H.A. J. Med. Genet. (1999) [Pubmed]
  2. Fine mapping of the 2p11 dyslexia locus and exclusion of TACR1 as a candidate gene. Peyrard-Janvid, M., Anthoni, H., Onkamo, P., Lahermo, P., Zucchelli, M., Kaminen, N., Hannula-Jouppi, K., Nopola-Hemmi, J., Voutilainen, A., Lyytinen, H., Kere, J. Hum. Genet. (2004) [Pubmed]
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