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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TMEM200A  -  transmembrane protein 200A

Homo sapiens

Synonyms: HBE61, KIAA1913, TTMA, TTMC, Transmembrane protein 200A
 
 
 
 
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Disease relevance of KIAA1913

  • 1. Frequent detection of reduced expression of AK091351 and KIAA1913 genes implicates them as suppressors of medulloblastoma tumorigenesis [1].
 

High impact information on KIAA1913

  • Quantitative reverse transcription-PCR analysis showed complete loss of expression of two genes located at 6q23.1, AK091351 (hypothetical protein FLJ34032) and KIAA1913, in the cell line DAOY. mRNA levels of these genes was reduced in cell lines D283 and D384, and in 50% and 70% of primary tumors, respectively [1].

References

  1. Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis. Hui, A.B., Takano, H., Lo, K.W., Kuo, W.L., Lam, C.N., Tong, C.Y., Chang, Q., Gray, J.W., Ng, H.K. Clin. Cancer Res. (2005) [Pubmed]
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