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Gene Review:

RNU86 - RNA, U86 small nucleolar

Homo sapiens

Synonyms: U82, U86

Papanikolaou, E. et al., Filippini, D. et al.

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Disease relevance of RNU86

Identification and characterization of the gene products of open reading frame U86/87 of human herpesvirus 6 [1].

High impact information on RNU86

Despite the overall homology, the three U86 snoRNAs do not show strong conservation of the sequence upstream from the box D and none of them displays significant sequence complementarity to rRNA or snRNA sequences, suggesting a role different from that of methylation [2].
In this study, to characterize HHV-6 IE2 gene products, polyclonal antibodies against four domains of the U86/87 open reading frame were generated by immunization of rabbits with bacterially-expressed proteins [1].

References

Identification and characterization of the gene products of open reading frame U86/87 of human herpesvirus 6. Papanikolaou, E., Kouvatsis, V., Dimitriadis, G., Inoue, N., Arsenakis, M. Virus Res. (2002) [Pubmed]
U86, a novel snoRNA with an unprecedented gene organization in yeast. Filippini, D., Renzi, F., Bozzoni, I., Caffarelli, E. Biochem. Biophys. Res. Commun. (2001) [Pubmed]

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