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Zbtb7a  -  zinc finger and BTB domain containing 7a

Rattus norvegicus

Synonyms: Leukemia/lymphoma-related factor, Lrf, OCZF, Oczf, Osteoclast-derived zinc finger protein, ...
 
 
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High impact information on Zbtb7a

  • Transient transfection assays indicate that OCZF can repress transcription activity like other POZ domain proteins [1].
  • Furthermore, antisense but not sense phosphorothioate oligodeoxynucleotides (ODNs) for OCZF cDNA suppressed the formation of osteoclast-like multinucleated cells (MNCs) in bone marrow culture, whereas the same ODNs did not significantly affect the formation of macrophage polykaryons and mononuclear preosteoclast-like cells (POCs) [1].
  • Northern blot and in situ hybridization analysis showed OCZF mRNA at a high level in osteoclasts and kidney cells [1].

References

 
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