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Gene Review: 

bapA  -  BapA protein

Borrelia burgdorferi B31

 
 
 
 
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Disease relevance of bapA

  • A large majority of examined Lyme disease spirochaete isolates were demonstrated to contain one or both of the paralogous genes bapA and eppA [1].
  • Immunological and genetic characterization of Borrelia burgdorferi BapA and EppA proteins [1].
 

Analytical, diagnostic and therapeutic context of bapA

  • Immunological analyses of serum samples collected from infected patients coupled with comparative sequence analyses indicated that bapA gene sequences are quite stable but the encoded proteins do not provoke a strong immune response in most individuals [1].

References

  1. Immunological and genetic characterization of Borrelia burgdorferi BapA and EppA proteins. Miller, J.C., Stevenson, B. Microbiology (Reading, Engl.) (2003) [Pubmed]
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