The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

CLN4  -  ceroid-lipofuscinosis, neuronal 4 (Kufs...

Homo sapiens

This record was replaced with 80331.
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on CLN4

  • NCLs are caused by at least 8 mutant genes (CLN1-CLN8), though CLN4 and CLN7 have not yet been identified [1].
  • The genes for classic late-infantile neuronal ceroid-lipofuscinosis, CLN2, and for adult neuronal ceroid-lipofuscinosis, CLN4, have not been located, the former having been excluded from chromosomes 1 and 16 [2].
  • Two cases were of the infantile type (CLN1), one case of the juvenile (CLN3) type and one case of the adult (CLN4) type [3].


  1. The intracellular location and function of proteins of neuronal ceroid lipofuscinoses. Ezaki, J., Kominami, E. Brain Pathol. (2004) [Pubmed]
  2. The neuronal ceroid-lipofuscinoses. Goebel, H.H. J. Child Neurol. (1995) [Pubmed]
  3. Neuronal ceroid lipofuscinosis in the Czech Republic: analysis of 57 cases. Report of the 'Prague NCL group'. Elleder, M., Franc, J., Kraus, J., Nevsímalová, S., Sixtová, K., Zeman, J. Eur. J. Paediatr. Neurol. (1997) [Pubmed]
WikiGenes - Universities