Gene Review:
vsrA - transmembrane sensor kinase vsrA...
Ralstonia solanacearum GMI1000
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Disease relevance of vsrA
- PhoA fusion analysis and subcellular localization of the vsrA gene product in Escherichia coli maxicells suggest that it is a 53 kDa membrane-associated protein [1].
High impact information on vsrA
- Analysis of the nucleotide sequence of vsrA revealed a 502 residue open reading frame with homology to the histidine kinase domain of sensors in the two-component regulator family [1].
- This correlated with a greater than 10-fold reduction in their ability to grow in planta. vsrA was cloned from a P. solanacearum genomic library by complementation of the vsrA mutant and was further subcloned on a 2.3 kb DNA fragment [1].
References
- VsrA, a second two-component sensor regulating virulence genes of Pseudomonas solanacearum. Schell, M.A., Denny, T.P., Huang, J. Mol. Microbiol. (1994) [Pubmed]
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