The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Genomic Library

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Genomic Library


High impact information on Genomic Library


Chemical compound and disease context of Genomic Library


Biological context of Genomic Library


Anatomical context of Genomic Library


Associations of Genomic Library with chemical compounds

  • A copy of this element has been recovered from a Glycine max genomic library [26].
  • A series of cosmid clones was isolated from a human genomic library by using a probe encoding part of the fourth component of complement, C4 [27].
  • A genomic library of P. testosteroni total DNA constructed from partial EcoRI digests ligated to a lambda gtWES vector was probed with a 23-base oligonucleotide mixture [ATGAAC(T)ACC(A,T)CCG(C,A)GAG(A)CAC(T)ATGAC] corresponding to the NH2-terminal sequence of steroid isomerase [28].
  • First, a mouse AcChoR alpha-subunit cDNA probe was used to screen a size-selected snake (Natrix tessellata) genomic library [29].
  • Uracil prototrophs resulting from transformation with a multicopy YEp24 yeast genomic library were screened, leading to the identification of transformants possessing high levels of glycosidase activity [30].

Gene context of Genomic Library


Analytical, diagnostic and therapeutic context of Genomic Library


  1. Yeast DNA topoisomerase II is encoded by a single-copy, essential gene. Goto, T., Wang, J.C. Cell (1984) [Pubmed]
  2. Selective amplification of an mRNA and related pseudogene for a human ADP-ribosylation factor, a guanine nucleotide-dependent protein activator of cholera toxin. Monaco, L., Murtagh, J.J., Newman, K.B., Tsai, S.C., Moss, J., Vaughan, M. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  3. Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants. Bookstein, R., Lee, E.Y., To, H., Young, L.J., Sery, T.W., Hayes, R.C., Friedmann, T., Lee, W.H. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  4. A genetic screen for the identification of thiamin metabolic genes. Lawhorn, B.G., Gerdes, S.Y., Begley, T.P. J. Biol. Chem. (2004) [Pubmed]
  5. Complete nucleotide sequence and characterization of the 5'-flanking region of mammalian elongation factor 2 gene. Nakanishi, T., Kohno, K., Ishiura, M., Ohashi, H., Uchida, T. J. Biol. Chem. (1988) [Pubmed]
  6. Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development. Deutsch, U., Dressler, G.R., Gruss, P. Cell (1988) [Pubmed]
  7. Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements. Shore, D., Nasmyth, K. Cell (1987) [Pubmed]
  8. Remarkable conservation of structure among intermediate filament genes. Marchuk, D., McCrohon, S., Fuchs, E. Cell (1984) [Pubmed]
  9. The Drosophila gene knirps-related is a member of the steroid-receptor gene superfamily. Oro, A.E., Ong, E.S., Margolis, J.S., Posakony, J.W., McKeown, M., Evans, R.M. Nature (1988) [Pubmed]
  10. The human gene encoding GM-CSF is at 5q21-q32, the chromosome region deleted in the 5q- anomaly. Huebner, K., Isobe, M., Croce, C.M., Golde, D.W., Kaufman, S.E., Gasson, J.C. Science (1985) [Pubmed]
  11. Cloning, sequencing, and expression of the Escherichia coli peptide methionine sulfoxide reductase gene. Rahman, M.A., Nelson, H., Weissbach, H., Brot, N. J. Biol. Chem. (1992) [Pubmed]
  12. An ABC-transporter from Streptomyces longisporoflavus confers resistance to the polyether-ionophore antibiotic tetronasin. Linton, K.J., Cooper, H.N., Hunter, I.S., Leadlay, P.F. Mol. Microbiol. (1994) [Pubmed]
  13. The Legionella (Fluoribacter) gormanii metallo-beta-lactamase: a new member of the highly divergent lineage of molecular-subclass B3 beta-lactamases. Boschi, L., Mercuri, P.S., Riccio, M.L., Amicosante, G., Galleni, M., Frère, J.M., Rossolini, G.M. Antimicrob. Agents Chemother. (2000) [Pubmed]
  14. Characterization of the gene celD and its encoded product 1,4-beta-D-glucan glucohydrolase D from Pseudomonas fluorescens subsp. cellulosa. Rixon, J.E., Ferreira, L.M., Durrant, A.J., Laurie, J.I., Hazlewood, G.P., Gilbert, H.J. Biochem. J. (1992) [Pubmed]
  15. Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene. Margolis, P.S., Hackbarth, C.J., Young, D.C., Wang, W., Chen, D., Yuan, Z., White, R., Trias, J. Antimicrob. Agents Chemother. (2000) [Pubmed]
  16. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. Xie, Q.W., Whisnant, R., Nathan, C. J. Exp. Med. (1993) [Pubmed]
  17. Expression of complement proteins C2 and factor B in transfected L cells. Perlmutter, D.H., Colten, H.R., Grossberger, D., Strominger, J., Seidman, J.G., Chaplin, D.D. J. Clin. Invest. (1985) [Pubmed]
  18. Cloning and functional characterization of the rat stomach fundus serotonin receptor. Foguet, M., Hoyer, D., Pardo, L.A., Parekh, A., Kluxen, F.W., Kalkman, H.O., Stühmer, W., Lübbert, H. EMBO J. (1992) [Pubmed]
  19. A complex gene superfamily encodes actin in petunia. Baird, W.V., Meagher, R.B. EMBO J. (1987) [Pubmed]
  20. The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein. Kitamura, K., Shimoda, C. EMBO J. (1991) [Pubmed]
  21. Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family. Schiff, C., Milili, M., Fougereau, M. EMBO J. (1985) [Pubmed]
  22. Molecular cloning and characterization of human pyruvate dehydrogenase beta subunit gene. Koike, K., Urata, Y., Koike, M. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  23. Primary structure of the human follistatin precursor and its genomic organization. Shimasaki, S., Koga, M., Esch, F., Cooksey, K., Mercado, M., Koba, A., Ueno, N., Ying, S.Y., Ling, N., Guillemin, R. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  24. Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Cook, J.S., Lucas, J.J., Sibley, E., Bolanowski, M.A., Christy, R.J., Kelly, T.J., Lane, M.D. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  25. Strong evolutionary conservation of neuropeptide Y: sequences of chicken, goldfish, and Torpedo marmorata DNA clones. Blomqvist, A.G., Söderberg, C., Lundell, I., Milner, R.J., Larhammar, D. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  26. SIRE-1, a copia/Ty1-like retroelement from soybean, encodes a retroviral envelope-like protein. Laten, H.M., Majumdar, A., Gaucher, E.A. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  27. Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man. White, P.C., Grossberger, D., Onufer, B.J., Chaplin, D.D., New, M.I., Dupont, B., Strominger, J.L. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  28. Isolation and sequencing of the gene encoding delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni: overexpression of the protein. Kuliopulos, A., Shortle, D., Talalay, P. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  29. Snake acetylcholine receptor: cloning of the domain containing the four extracellular cysteines of the alpha subunit. Neumann, D., Barchan, D., Horowitz, M., Kochva, E., Fuchs, S. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  30. Cloning and heterologous expression of glycosidase genes from Saccharomyces cerevisiae. Kuranda, M.J., Robbins, P.W. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  31. Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. He, F., Jacobson, A. Genes Dev. (1995) [Pubmed]
  32. Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones. Hudson, P., John, M., Crawford, R., Haralambidis, J., Scanlon, D., Gorman, J., Tregear, G., Shine, J., Niall, H. EMBO J. (1984) [Pubmed]
  33. Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III. Boulet, A., Simon, M., Faye, G., Bauer, G.A., Burgers, P.M. EMBO J. (1989) [Pubmed]
  34. Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes. Sneddon, A.A., Cohen, P.T., Stark, M.J. EMBO J. (1990) [Pubmed]
  35. Genomic structure of the human retinoblastoma-related Rb2/p130 gene. Baldi, A., Boccia, V., Claudio, P.P., De Luca, A., Giordano, A. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  36. Molecular cloning and functional expression of a brain-specific somatostatin receptor. Bruno, J.F., Xu, Y., Song, J., Berelowitz, M. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  37. Chromosomal localization of several families of repetitive sequences by in situ hybridization. Devine, E.A., Nolin, S.L., Houck, G.E., Jenkins, E.C., Brown, W.T. Am. J. Hum. Genet. (1985) [Pubmed]
  38. Identification and characterization of PF4varl, a human gene variant of platelet factor 4. Green, C.J., Charles, R.S., Edwards, B.F., Johnson, P.H. Mol. Cell. Biol. (1989) [Pubmed]
  39. Unusual DNA sequences located within the promoter region and the first intron of the chicken pro-alpha 1(I) collagen gene. Finer, M.H., Aho, S., Gerstenfeld, L.C., Boedtker, H., Doty, P. J. Biol. Chem. (1987) [Pubmed]
  40. Sequence of the sodium ion pump oxaloacetate decarboxylase from Salmonella typhimurium. Woehlke, G., Wifling, K., Dimroth, P. J. Biol. Chem. (1992) [Pubmed]
WikiGenes - Universities