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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

occR  -  hypothetical protein

Agrobacterium tumefaciens

 
 
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High impact information on occR

  • Primer extension analysis showed that OccR protein represses the occR gene and both represses and activates the occQ operon, which is divergently transcribed from occR [1].
  • The other two occR mutations cause the protein to detect much lower concentrations of octopine than wild-type OccR protein does [2].
  • We propose the names nocR and occR for the regulator genes in the noc and in the occ regions [3].
 

Other interactions of occR

  • To understand better the mechanism of activation of OccR, we isolated mutations both in the occQ promoter and in the occR gene which function differently from the wild type [2].

References

  1. The A. tumefaciens transcriptional activator OccR causes a bend at a target promoter, which is partially relaxed by a plant tumor metabolite. Wang, L., Helmann, J.D., Winans, S.C. Cell (1992) [Pubmed]
  2. Altered-function mutations in the Agrobacterium tumefaciens OccR protein and in an OccR-regulated promoter. Cho, K., Winans, S.C. J. Bacteriol. (1993) [Pubmed]
  3. Positive regulators of opine-inducible promoters in the nopaline and octopine catabolism regions of Ti plasmids. von Lintig, J., Zanker, H., Schröder, J. Mol. Plant Microbe Interact. (1991) [Pubmed]
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