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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Genes, Regulator

 
 
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Disease relevance of Genes, Regulator

 

Psychiatry related information on Genes, Regulator

 

High impact information on Genes, Regulator

 

Chemical compound and disease context of Genes, Regulator

 

Biological context of Genes, Regulator

 

Anatomical context of Genes, Regulator

 

Associations of Genes, Regulator with chemical compounds

  • Thus, ATR1 defines the first characterized tryptophan gene regulator in plants, and the atr1D mutation defines a sequence important for ATR1 expression [27].
  • This fusion did not map in any of the known genes of the malA or malB region, but its expression was under control of malT, the positive regulator gene of the maltose regulon [28].
  • Activation of transcription at divergent urea-dependent promoters by the urease gene regulator UreR [29].
  • Sequence analysis of a cloned 5.5-kb DNA fragment obtained from 1 of the imipenem-resistant E. asburiae isolates identified an upstream LysR-type regulator gene that explained inducibility of IMI-2 expression. beta-Lactamase IMI-2 is the first inducible and plasmid-encoded carbapenemase [30].
  • Distribution of mec regulator genes in methicillin-resistant Staphylococcus clinical strains [31].
 

Gene context of Genes, Regulator

  • Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development [32].
  • Furthermore, these mice had a 24-hour lag in the hepatic expression of the G(1)/S checkpoint regulator genes Ccnd1 and cMyc and increased expression of the IL-1beta cytokine gene [33].
  • Endotoxin treatment of rats and interleukin-1 beta (IL-1 beta) treatment of liver-derived HepG2 cells leads to a marked decline in the nuclear binding activity of a main Ntcp gene regulator, the nuclear receptor heterodimer retinoid X receptor:retinoic acid receptor (RXR:RAR) [34].
  • These nuclear receptors play crucial roles in the regulation of fatty acid metabolism: LXRs activate expression of sterol regulatory element-binding protein 1c (SREBP-1c), a dominant lipogenic gene regulator, whereas PPARalpha promotes fatty acid beta-oxidation genes [35].
  • A 560 bp intergenic region upstream of the nuo locus was followed by a gene (designated lrhA for LysR homologue A) coding for a gene regulator similar to those of the LysR family [36].
 

Analytical, diagnostic and therapeutic context of Genes, Regulator

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