Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

vapD - VapD

Rhodococcus equi

Benoit, S. et al., Benoit, S. et al.

Benoit, Benachour, Taouji, Auffray, Hartke,

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High impact information on vapD

Since our results showed that vapA, vapD, and vapG are genes highly induced by macrophage-related stresses, their gene products may, within the Vap protein family, play a dominant role inside these phagocytic cells and may be the most promising candidates for vaccination strategies [1].

Biological context of vapD

0. One operon, containing vapA, was monocistronic whereas the other was polycistronic composed of vapD and an unknown open reading frame [2].

Other interactions of vapD

Alignment of this sequence with the leader sequences of vapA and vapD, genes previously shown to be induced by acid, revealed significant homologies [1].

References

H(2)O(2), which causes macrophage-related stress, triggers induction of expression of virulence-associated plasmid determinants in Rhodococcus equi. Benoit, S., Benachour, A., Taouji, S., Auffray, Y., Hartke, A. Infect. Immun. (2002) [Pubmed]
Induction of vap genes encoded by the virulence plasmid of Rhodococcus equi during acid tolerance response. Benoit, S., Benachour, A., Taouji, S., Auffray, Y., Hartke, A. Res. Microbiol. (2001) [Pubmed]

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