Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

nadD - nicotinate-nucleotide adenylyltransferase

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Hughes, K.T. et al., Foster, J.W. et al.

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High impact information on nadD

(iii) nadD mutants have mutations that affect a new gene involved in pyridine nucleotide metabolism [1].
Since a high proportion of nadD mutations are temperature-sensitive lethal mutations, this appears to be an essential gene for NAD and NADP biosynthesis [1].
Secondary mutations which suppress the Pas- phenotype were found to reside in the following NAD-related loci; pncB, nadB and nadD [2].

References

6-Aminonicotinamide-resistant mutants of Salmonella typhimurium. Hughes, K.T., Cookson, B.T., Ladika, D., Olivera, B.M., Roth, J.R. J. Bacteriol. (1983) [Pubmed]
NAD metabolism in Salmonella typhimurium: isolation of pyridine analogue supersensitive (pas) and pas suppressor mutants. Foster, J.W., Holley, E.A., Mya, S. J. Gen. Microbiol. (1984) [Pubmed]

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