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Gene Review

rfbP  -  undecaprenyl-phosphate galactose...

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

 
 
 
 
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Disease relevance of rfbP

  • Nucleotide sequencing of DNA flanking the insertion site in COH1-13 revealed an open reading frame, designated cpsD, with significant homology to the rfbP gene of Salmonella typhimurium [1].
 

High impact information on rfbP

  • These results, together with the similarity in deduced amino acid sequence between cpsD and rfbP suggest that cpsD encodes a galactosyl transferase essential for assembly of the GBS type III capsular polysaccharide [1].

References

  1. Identification of cpsD, a gene essential for type III capsule expression in group B streptococci. Rubens, C.E., Heggen, L.M., Haft, R.F., Wessels, M.R. Mol. Microbiol. (1993) [Pubmed]
 
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