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Gene Review:

fljA - phase-1 flagellin repressor

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Inoue, Y.H. et al., Yamamoto, S. et al.

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Disease relevance of fljA

In phase-2 cells of diphasic Salmonella strains, expression of the phase-1 flagellin-encoding gene, fliC, is repressed by the repressor encoded by the fljA gene [1].

High impact information on fljA

The fljB gene constitutes an operon with the fljA gene, which encodes a negative regulator for fliC expression [2].

References

Sequence analysis of operator mutants of the phase-1 flagellin-encoding gene, fliC, in Salmonella typhimurium. Inoue, Y.H., Kutsukake, K., Iino, T., Yamaguchi, S. Gene (1989) [Pubmed]
FljA-mediated posttranscriptional control of phase 1 flagellin expression in flagellar phase variation of Salmonella enterica serovar Typhimurium. Yamamoto, S., Kutsukake, K. J. Bacteriol. (2006) [Pubmed]

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