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Gene Review

31.2  -  gp31.2 hypothetical protein

Enterobacteria phage T4

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High impact information on 31.2

  • From the original pool of patients, we classified 56 TBII negative patients into two groups according to the clinical course taken; Group A in whom TBII remained undetectable throughout methimazole treatment (9 men and 34 women, age 37.2 +/- 2.2 years), and Group B who became TBII positive (4 men and 9 women, 31.2 +/- 4.4 years) [1].
  • SHBG concentration rose from 38.1 +/- 18.3 to 54.3 +/- 16.0 nmol/l (P less than 0.01), while T and E2 showed significant increases from 31.2 +/- 10.8 nmol/l and 24.6 +/- 5.4 pg/ml to 52.0 +/- 3.6 and 43.3 +/- 14.9, respectively in the oligozoospermic patients, with similar rises noted in the normospermic men [2].
  • However, it induced an important increment of 5'-ID-I in the thyroid gland (0.8 times higher than that of the normal group: control = 131.9 +/- 23.7 vs OVX + EB 14 micrograms = 248.0 +/- 31.2; P < 0.05), which is associated with increased serum TSH (0.6-fold vs OVX, P < 0.05) but normal serum free T3 and free T4 [3].


  1. A study of untreated Graves' patients with undetectable TSH binding inhibitor immunoglobulins and the effect of anti-thyroid drugs. Kawai, K., Tamai, H., Matsubayashi, S., Mukuta, T., Morita, T., Kubo, C., Kuma, K. Clin. Endocrinol. (Oxf) (1995) [Pubmed]
  2. The effect of clomiphene citrate on sex hormone binding globulin in normospermic and oligozoospermic men. Adamopoulos, D.A., Vassilopoulos, P., Kapolla, N., Kontogeorgos, L. Int. J. Androl. (1981) [Pubmed]
  3. Effects of estradiol benzoate on 5'-iodothyronine deiodinase activities in female rat anterior pituitary gland, liver and thyroid gland. Lisbôa, P.C., Curty, F.H., Moreira, R.M., Pazos-Moura, C.C. Braz. J. Med. Biol. Res. (1997) [Pubmed]
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