The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

CALR3  -  calreticulin 3

Homo sapiens

Synonyms: CMH19, CRT2, CT93, Calreticulin-2, Calreticulin-3, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of CALR3

  • Using the dot-blot method, we were able to detect C. rectus using the CRT-2 antibody when as few as 103 organisms were present in a subgingival dental plaque sample [1].
  • CRT2 was identified as a new cancer-testis antigen expressed in elongated spermatids of testis and in cancer tissues (particularly melanoma) that is recognized by serum IgG from cancer patients [2].

High impact information on CALR3

  • Translation of the CRT2 coding sequence reveals a new protein with regions of perfect homology with the CRT1 amino-acid sequence [3].


  1. Detection of Campylobacter rectus in periodontitis sites by monoclonal antibodies. Ihara, H., Miura, T., Kato, T., Ishihara, K., Nakagawa, T., Yamada, S., Okuda, K. J. Periodont. Res. (2003) [Pubmed]
  2. Identification of a novel cancer-testis antigen CRT2 frequently expressed in various cancers using representational differential analysis. Hayashi, E., Matsuzaki, Y., Hasegawa, G., Yaguchi, T., Kurihara, S., Fujita, T., Kageshita, T., Sano, M., Kawakami, Y. Clin. Cancer Res. (2007) [Pubmed]
  3. Cloning and sequencing of a cDNA encoding a novel member of the human brain GABA/noradrenaline neurotransmitter transporter family. Barnwell, L.F., Chaudhuri, G., Townsel, J.G. Gene (1995) [Pubmed]
WikiGenes - Universities