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Gene Review:

CNN2 - calponin 2

Homo sapiens

Synonyms: Calponin H2, smooth muscle, Calponin-2, Neutral calponin

Masuda, H. et al., Tang, J. et al.

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High impact information on CNN2

Calponin 2 (h2 calponin, CNN2) is an actin-binding protein implicated in cytoskeletal organization [1].
On the basis of the nucleotide sequence identity to an expressed sequence tag, HUM21ES93 [Cheng, J.-F., Boyartchuk, V., and Zhu, Y. (1994) Genomics 23, 75-84], the human neutral calponin gene is assigned to chromosome 21q11 [2].

References

A critical role for calponin 2 in vascular development. Tang, J., Hu, G., Hanai, J., Yadlapalli, G., Lin, Y., Zhang, B., Galloway, J., Bahary, N., Sinha, S., Thisse, B., Thisse, C., Jin, J.P., Zon, L.I., Sukhatme, V.P. J. Biol. Chem. (2006) [Pubmed]
Molecular cloning and characterization of human non-smooth muscle calponin. Masuda, H., Tanaka, K., Takagi, M., Ohgami, K., Sakamaki, T., Shibata, N., Takahashi, K. J. Biochem. (1996) [Pubmed]

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