Gene Review:
EDARADD - EDAR-associated death domain
Homo sapiens
Synonyms:
ECTD11A, ECTD11B, ED3, EDA3, EDAR-associated death domain protein, ...
- Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Headon, D.J., Emmal, S.A., Ferguson, B.M., Tucker, A.S., Justice, M.J., Sharpe, P.T., Zonana, J., Overbeek, P.A. Nature (2001)
- TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd. Morlon, A., Munnich, A., Smahi, A. Hum. Mol. Genet. (2005)
- A rare case of hypohidrotic ectodermal dysplasia caused by compound heterozygous mutations in the EDAR gene. Shimomura, Y., Sato, N., Miyashita, A., Hashimoto, T., Ito, M., Kuwano, R. J. Invest. Dermatol. (2004)