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Gene Review

Defa-rs2  -  defensin, alpha, related sequence 2

Mus musculus

Synonyms: Alpha-defensin-related sequence 2, CRS4C, CRS4C-1, CRS4C1, CRS4C1d, ...
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High impact information on Defcr-rs2

  • Nucleotide sequences corresponding to the deduced prepro-coding regions of cryptdin, CRS1C, and CRS4C mRNAs contain a highly conserved 200-base pair region of 92% sequence similarity (CSE.2), but the mRNAs are not homologous otherwise [1].
  • Attempts to find homologies between the putative CRS peptides and existing protein sequences have been unsuccessful, leading us to speculate that CRS1C and CRS4C represent a new family of nondefensin antimicrobial peptides in the mouse small bowel [1].

Biological context of Defcr-rs2


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