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Gene Review

H1FOO  -  H1 histone family, member O, oocyte-specific

Homo sapiens

Synonyms: H1.8, H1OO, Histone H1oo, OSH1, Oocyte-specific histone H1, ...
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High impact information on H1FOO

  • The gene, named osH1, included five exons as predicted by the NCBI annotation project of the human genome, although the actual splicing site at the 3(') end of exon 3 was different by 48 nucleotides from the prediction [1].
  • The presence of polyadenylation signals and successful amplification of cDNA by RT-PCR using an oligo(dT) primer suggested that the osH1 mRNA is polyadenylated unlike somatic H1 mRNA [1].


  1. Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte. Tanaka, Y., Kato, S., Tanaka, M., Kuji, N., Yoshimura, Y. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
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