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Gene Review

Plxnb3  -  plexin B3

Mus musculus

Synonyms: AI451018, Kiaa1206, Plexin-6, Plexin-B3, Plxn6
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High impact information on Plxnb3

  • We have previously shown that plexin B3 is a highly potent stimulator of neurite outgrowth, which makes its gene PLXNB3 an intriguing candidate gene for traits related to human brain development and cerebral connectivity [1].

Anatomical context of Plxnb3

  • These findings suggest that plexin B3 may influence cognitive performance, and the development of white matter in vivo in a way similar to its known stimulating effect on neurite outgrowth in vitro [1].


  1. Plexin B3 is genetically associated with verbal performance and white matter volume in human brain. Rujescu, D., Meisenzahl, E.M., Krejcova, S., Giegling, I., Zetzsche, T., Reiser, M., Born, C.M., Möller, H.J., Veske, A., Gal, A., Finckh, U. Mol. Psychiatry (2007) [Pubmed]
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