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Gene Review

SYT9  -  synaptotagmin IX

Homo sapiens

Synonyms: Synaptotagmin IX, Synaptotagmin-9, SytIX
 
 
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Disease relevance of SYT9

 

High impact information on SYT9

  • Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules [2].
 

Biological context of SYT9

  • Neither Snapin nor Syt IX affected channel function, but they notably inhibited protein kinase C (PKC)-induced potentiation of TRPV1 channel activity with a potency that rivaled the blockade evoked by botulinum neurotoxin A, a potent blocker of neuronal exocytosis [1].

References

  1. Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. Morenilla-Palao, C., Planells-Cases, R., García-Sanz, N., Ferrer-Montiel, A. J. Biol. Chem. (2004) [Pubmed]
  2. Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules. Haberman, Y., Grimberg, E., Fukuda, M., Sagi-Eisenberg, R. J. Cell. Sci. (2003) [Pubmed]
 
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