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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PH1622  -  ATP-dependent DNA ligase

Pyrococcus horikoshii OT3

 
 
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Disease relevance of PH1622

  • Archaea encode a DNA ligase composed of a C-terminal catalytic domain typical of ATP-dependent ligases plus an N-terminal domain similar to that found in eukaryotic cellular and poxvirus DNA ligases [1].

References

  1. Characterization of a thermophilic ATP-dependent DNA ligase from the euryarchaeon Pyrococcus horikoshii. Keppetipola, N., Shuman, S. J. Bacteriol. (2005) [Pubmed]
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