Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

orf8 - putative regulator

Escherichia coli

Nassau, P.M. et al., Wing, C. et al.

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Disease relevance of orf8

Cloning of E. coli K-12 orf8 (wbbI) and over-expression of the corresponding enzyme as a maltose-binding fusion protein provided recombinant WbbI beta-1,6-galactofuranosyltransferase activity [1].

High impact information on orf8

No mutase activity was detected in extracts from cells lacking the orf6 expression plasmid or from orf8-expressing cells [2].

Biological context of orf8

We have cloned two open reading frames (orf6 and orf8) from the Escherichia coli K-12 rfb region [2].

References

Expression and initial characterization of WbbI, a putative d-Galf:alpha-d-Glc beta-1,6-galactofuranosyltransferase from Escherichia coli K-12. Wing, C., Errey, J.C., Mukhopadhyay, B., Blanchard, J.S., Field, R.A. Org. Biomol. Chem. (2006) [Pubmed]
Galactofuranose biosynthesis in Escherichia coli K-12: identification and cloning of UDP-galactopyranose mutase. Nassau, P.M., Martin, S.L., Brown, R.E., Weston, A., Monsey, D., McNeil, M.R., Duncan, K. J. Bacteriol. (1996) [Pubmed]

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