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Gene Review:

AtHV3gp01 - TIO; similar to TIP and STP-C of...

Ateline herpesvirus 3

Albrecht, J.C. et al., Albrecht, J.C. et al.

Albrecht, Biesinger, Müller-Fleckenstein, Lengenfelder, Schmidt, Fleckenstein, Ensser, Albrecht,

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Disease relevance of AtHV3gp01

The left terminal region of the light DNA segment bears the putative rhadinovirus oncogene tio [1].

High impact information on AtHV3gp01

We inserted the tio sequence of herpesvirus ateles strain 73 into a recombinant herpesvirus saimiri C488 lacking its own stpC/tip oncogene [2].

References

Primary structure of the Herpesvirus ateles genome. Albrecht, J.C. J. Virol. (2000) [Pubmed]
Herpesvirus ateles Tio can replace herpesvirus saimiri StpC and Tip oncoproteins in growth transformation of monkey and human T cells. Albrecht, J.C., Biesinger, B., Müller-Fleckenstein, I., Lengenfelder, D., Schmidt, M., Fleckenstein, B., Ensser, A. J. Virol. (2004) [Pubmed]

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