Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

GSHVgp1 - core antigen

Ground squirrel hepatitis virus

Stuyver, L. et al., Vilja, P. et al., Trevisan, A. et al., Ponzetto, A. et al., Howard, C.R. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of GSHVgp1

Core antigen-specific immunoglobulin G bound to the liver cell membrane in chronic hepatitis B [1].
Core antigen and antibody in woodchucks after infection with woodchuck hepatitis virus [2].
Core antigen produced in Escherichia coli was labeled with biotin and subsequently detected by an avidin-biotin-peroxidase complex [3].
Core antigen and circulating anti-core antibody in hepatitis B infection [4].

High impact information on GSHVgp1

All virus strains analysed contained some characteristic differences when compared to genotype A: a translational stop codon at aa 2 and 28 of the preCore region; a 36 nt (12 aa) insert in the amino-terminal part of the Core antigen (HBcAg); a 2 aa deletion in the carboxy-terminal part of HBcAg; and a 1 aa deletion in the preS1 open reading frame [5].

References

Core antigen-specific immunoglobulin G bound to the liver cell membrane in chronic hepatitis B. Trevisan, A., Realdi, G., Alberti, A., Ongaro, G., Pornaro, E., Meliconi, R. Gastroenterology (1982) [Pubmed]
Core antigen and antibody in woodchucks after infection with woodchuck hepatitis virus. Ponzetto, A., Cote, P.J., Ford, E.C., Purcell, R.H., Gerin, J.L. J. Virol. (1984) [Pubmed]
Determination of immunoglobulin M antibodies for hepatitis B core antigen with a capture enzyme immunoassay and biotin-labeled core antigen produced in Escherichia coli. Vilja, P., Turunen, H.J., Leinikki, P.O. J. Clin. Microbiol. (1985) [Pubmed]
Core antigen and circulating anti-core antibody in hepatitis B infection. Howard, C.R., Zuckerman, A.J. J. Immunol. Methods (1977) [Pubmed]
A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness. Stuyver, L., De Gendt, S., Van Geyt, C., Zoulim, F., Fried, M., Schinazi, R.F., Rossau, R. J. Gen. Virol. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.