The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Hepatitis B

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Hepatitis B


Psychiatry related information on Hepatitis B


High impact information on Hepatitis B

  • Lamivudine in the treatment of acute hepatitis B [11].
  • CONCLUSIONS: Since the institution of Taiwan's program of universal hepatitis B vaccination, the incidence of hepatocellular carcinoma in children has declined [5].
  • Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia [12].
  • The 87 nucleotides in the precore region of the hepatitis B virus were amplified by the polymerase chain reaction and then directly sequenced [13].
  • The presence of HBV was identified by polymerase-chain-reaction amplification of viral DNA in serum from the source patient, the five patients with fulminant hepatitis B, and five controls with acute, self-limited hepatitis B [14].

Chemical compound and disease context of Hepatitis B


Biological context of Hepatitis B


Anatomical context of Hepatitis B


Gene context of Hepatitis B


Analytical, diagnostic and therapeutic context of Hepatitis B


  1. Deleterious effect of prednisolone in HBsAg-positive chronic active hepatitis. Lam, K.C., Lai, C.L., Trepo, C., Wu, P.C. N. Engl. J. Med. (1981) [Pubmed]
  2. Polymerase chain reaction to detect hepatitis B virus DNA and RNA sequences in primary liver cancers from patients negative for hepatitis B surface antigen. Paterlini, P., Gerken, G., Nakajima, E., Terre, S., D'Errico, A., Grigioni, W., Nalpas, B., Franco, D., Wands, J., Kew, M. N. Engl. J. Med. (1990) [Pubmed]
  3. Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen. Bréchot, C., Degos, F., Lugassy, C., Thiers, V., Zafrani, S., Franco, D., Bismuth, H., Trépo, C., Benhamou, J.P., Wands, J. N. Engl. J. Med. (1985) [Pubmed]
  4. Absence of effect of zidovudine on replication of hepatitis B virus in patients with chronic HIV and HBV infection. Marcellin, P., Pialoux, G., Girard, P.M., Boyer, N., Martinot-Peignoux, M., Loriot, M.A., Dazza, M.C., Benhamou, J.P. N. Engl. J. Med. (1989) [Pubmed]
  5. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. Chang, M.H., Chen, C.J., Lai, M.S., Hsu, H.M., Wu, T.C., Kong, M.S., Liang, D.C., Shau, W.Y., Chen, D.S. N. Engl. J. Med. (1997) [Pubmed]
  6. Elevated serum testosterone levels and risk of hepatocellular carcinoma. Yu, M.W., Chen, C.J. Cancer Res. (1993) [Pubmed]
  7. Primary care of adults with mental retardation. Tyler, C.V., Bourguet, C. The Journal of family practice. (1997) [Pubmed]
  8. Hepatitis C tested prevalence and comorbidities among veterans in the US Northwest. Sloan, K.L., Straits-Tröster, K.A., Dominitz, J.A., Kivlahan, D.R. J. Clin. Gastroenterol. (2004) [Pubmed]
  9. Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis. A prospective study. Benvegnù, L., Fattovich, G., Noventa, F., Tremolada, F., Chemello, L., Cecchetto, A., Alberti, A. Cancer (1994) [Pubmed]
  10. Methadone treatment and HIV and hepatitis B and C risk reduction among injectors in the Seattle area. Thiede, H., Hagan, H., Murrill, C.S. Journal of urban health : bulletin of the New York Academy of Medicine. (2000) [Pubmed]
  11. Lamivudine in the treatment of acute hepatitis B. Reshef, R., Sbeit, W., Tur-Kaspa, R. N. Engl. J. Med. (2000) [Pubmed]
  12. Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia. Thursz, M.R., Kwiatkowski, D., Allsopp, C.E., Greenwood, B.M., Thomas, H.C., Hill, A.V. N. Engl. J. Med. (1995) [Pubmed]
  13. Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. Omata, M., Ehata, T., Yokosuka, O., Hosoda, K., Ohto, M. N. Engl. J. Med. (1991) [Pubmed]
  14. A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. Liang, T.J., Hasegawa, K., Rimon, N., Wands, J.R., Ben-Porath, E. N. Engl. J. Med. (1991) [Pubmed]
  15. Outbreak of severe hepatitis due to delta and hepatitis B viruses in parenteral drug abusers and their contacts. Lettau, L.A., McCarthy, J.G., Smith, M.H., Hadler, S.C., Morse, L.J., Ukena, T., Bessette, R., Gurwitz, A., Irvine, W.G., Fields, H.A. N. Engl. J. Med. (1987) [Pubmed]
  16. Steroid therapy in severe viral hepatitis. A double-blind, randomized trial of methyl-prednisolone versus placebo. Gregory, P.B., Knauer, C.M., Kempson, R.L., Miller, R. N. Engl. J. Med. (1976) [Pubmed]
  17. The hepatitis B virus-encoded transcriptional trans-activator hbx appears to be a novel protein serine/threonine kinase. Wu, J.Y., Zhou, Z.Y., Judd, A., Cartwright, C.A., Robinson, W.S. Cell (1990) [Pubmed]
  18. Induction of hepatitis B virus core gene in human cells by cytosine demethylation in the promoter. Korba, B.E., Wilson, V.L., Yoakum, G.H. Science (1985) [Pubmed]
  19. Hepatitis B "e" antigen: an apparent association with lactate dehydrogenase isozyme-5. Vyas, G.N., Peterson, D.L., Townsend, R.M., Damle, S.R., Magnius, L.O. Science (1977) [Pubmed]
  20. Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens. Shafritz, D.A., Shouval, D., Sherman, H.I., Hadziyannis, S.J., Kew, M.C. N. Engl. J. Med. (1981) [Pubmed]
  21. Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting. Chang, L.J., Pryciak, P., Ganem, D., Varmus, H.E. Nature (1989) [Pubmed]
  22. Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors. Seto, E., Mitchell, P.J., Yen, T.S. Nature (1990) [Pubmed]
  23. Hepatitis B virus contains pre-S gene-encoded domains. Neurath, A.R., Kent, S.B., Strick, N., Taylor, P., Stevens, C.E. Nature (1985) [Pubmed]
  24. A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma. de Thé, H., Marchio, A., Tiollais, P., Dejean, A. Nature (1987) [Pubmed]
  25. Integration of hepatitis B virus sequences and their expression in a human hepatoma cell. Edman, J.C., Gray, P., Valenzuela, P., Rall, L.B., Rutter, W.J. Nature (1980) [Pubmed]
  26. Protein transfer of preformed MHC-peptide complexes sensitizes target cells to T cell cytolysis. Huang, J.H., Getty, R.R., Chisari, F.V., Fowler, P., Greenspan, N.S., Tykocinski, M.L. Immunity (1994) [Pubmed]
  27. Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes. Kakimi, K., Lane, T.E., Wieland, S., Asensio, V.C., Campbell, I.L., Chisari, F.V., Guidotti, L.G. J. Exp. Med. (2001) [Pubmed]
  28. Mechanisms responsible for defective human T-lymphocyte sheep erythrocyte rosette function associated with hepatitis B virus infections. Chisari, F.V., Routenberg, J.A., Edgington, T.S. J. Clin. Invest. (1976) [Pubmed]
  29. Recombinant leukocyte a interferon treatment in patients with chronic hepatitis B virus infection. Pharmacokinetics, tolerance, and biologic effects. Omata, M., Imazeki, F., Yokosuka, O., Ito, Y., Uchiumi, K., Mori, J., Okuda, K. Gastroenterology (1985) [Pubmed]
  30. The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis. Lee, D.K., Park, S.H., Yi, Y., Choi, S.G., Lee, C., Parks, W.T., Cho, H., de Caestecker, M.P., Shaul, Y., Roberts, A.B., Kim, S.J. Genes Dev. (2001) [Pubmed]
  31. The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. Lara-Pezzi, E., Gómez-Gaviro, M.V., Gálvez, B.G., Mira, E., Iñiguez, M.A., Fresno, M., Martínez-A, C., Arroyo, A.G., López-Cabrera, M. J. Clin. Invest. (2002) [Pubmed]
  32. Tumor necrosis factor receptors in patients with chronic hepatitis B virus infection. Marinos, G., Naoumov, N.V., Rossol, S., Torre, F., Wong, P.Y., Gallati, H., Portmann, B., Williams, R. Gastroenterology (1995) [Pubmed]
  33. HBXIP functions as a cofactor of survivin in apoptosis suppression. Marusawa, H., Matsuzawa, S., Welsh, K., Zou, H., Armstrong, R., Tamm, I., Reed, J.C. EMBO J. (2003) [Pubmed]
  34. Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Wang, X.W., Forrester, K., Yeh, H., Feitelson, M.A., Gu, J.R., Harris, C.C. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  35. Acute viral hepatitis in adults. Comparison of the radioimmunoassay and counterimmunoelectrophoresis methods of detecting HbsAg. Wenzel, R.P., Teates, C.D., Galapon, Q., Barczak, R., Ling, C.M., Overby, L.R. JAMA (1975) [Pubmed]
  36. Hepatitis C virus infection among patients attending a clinic for sexually transmitted diseases. Weinstock, H.S., Bolan, G., Reingold, A.L., Polish, L.B. JAMA (1993) [Pubmed]
  37. Hepatitis B and C viruses and their interaction in the origin of hepatocellular carcinoma. Kaklamani, E., Trichopoulos, D., Tzonou, A., Zavitsanos, X., Koumantaki, Y., Hatzakis, A., Hsieh, C.C., Hatziyannis, S. JAMA (1991) [Pubmed]
  38. Epidemiology of hepatitis C virus. A preliminary study in volunteer blood donors. Stevens, C.E., Taylor, P.E., Pindyck, J., Choo, Q.L., Bradley, D.W., Kuo, G., Houghton, M. JAMA (1990) [Pubmed]
  39. Health status of refugees from Vietnam, Laos, and Cambodia. Catanzaro, A., Moser, R.J. JAMA (1982) [Pubmed]
WikiGenes - Universities