Gene Review:
waaF - ADP-heptose--lipooligosaccharide...
Haemophilus ducreyi 35000HP
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Disease relevance of waaF
- An open reading frame in H. ducreyi 35000 was found to encode a predicted protein that was 59% identical to the protein product of the rfaF (waaF) gene of Salmonella typhimurium [1].
High impact information on waaF
- Inactivation of the H. ducreyi waaF gene by insertion mutagenesis resulted in expression of a LOS that migrated much faster than wild-type LOS in sodium dodecyl sulfate-polyacrylamide gel electrophoresis [1].
References
- Characterization of a WaaF (RfaF) homolog expressed by Haemophilus ducreyi. Bauer, B.A., Lumbley, S.R., Hansen, E.J. Infect. Immun. (1999) [Pubmed]
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