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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Slc39a7  -  solute carrier family 39 (zinc...

Mus musculus

Synonyms: AA408174, AI117660, AL024048, H-2Ke4, H2-Ke4, ...
 
 
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High impact information on Slc39a7

  • A transcript of 2.8 kilobase pairs (K. Abe. J.-F. Wei, F.-S. Wei, Y.-C. Hsu, H. Uehara, K. Artzt, and D. Bennett, EMBO J. 7:3441-3449, 1988) encoded by the KE 4 gene flanking H-2K distally was identified [1].
  • The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus [2].
  • A putative 250-bp promoter, which is located between Rxrb and H2-Ke4, and may possibly be their common promoter, has also been identified [3].
  • Epitope-tagging experiments located ermelin and KE4 to a network structure throughout the cytoplasm [4].
  • Rxrb and H2-Ke4 are transcribed into opposite directions from a CpG-rich promoter of about 250 base pairs [5].

References

  1. A putative transmembrane protein with histidine-rich charge clusters encoded in the H-2K/tw5 region of mice. St-Jacques, B., Han, T.H., MacMurray, A., Shin, H.S. Mol. Cell. Biol. (1990) [Pubmed]
  2. The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus. Huang, L., Kirschke, C.P., Zhang, Y., Yu, Y.Y. J. Biol. Chem. (2005) [Pubmed]
  3. Characterization of mouse retinoid X receptor (RXR)-beta gene promoter: negative regulation by tumor necrosis factor (TNF)-alpha. Sugawara, A., Uruno, A., Nagata, T., Taketo, M.M., Takeuchi, K., Ito, S. Endocrinology (1998) [Pubmed]
  4. Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes. Suzuki, A., Endo, T. Gene (2002) [Pubmed]
  5. Physical mapping of the retinoid X receptor B gene in mouse and human. Nagata, T., Weiss, E.H., Abe, K., Kitagawa, K., Ando, A., Yara-Kikuti, Y., Seldin, M.F., Ozato, K., Inoko, H., Taketo, M. Immunogenetics (1995) [Pubmed]
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