The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

AWAT1  -  acyl-CoA wax alcohol acyltransferase 1

Homo sapiens

Synonyms: Acyl-CoA wax alcohol acyltransferase 1, DGA2, DGAT2L3, Diacylglycerol O-acyltransferase 2-like protein 3, Diacylglycerol acyltransferase 2, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on DGAT2L3

  • All four gene products mediate the synthesis of triacylglycerol; however, two of the X-linked genes act as acyl-CoA wax alcohol acyltransferases (AWAT 1 and 2) that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters [1].
  • In situ hybridizations demonstrate a differentiation-specific expression pattern within the human sebaceous gland for the two AWAT genes, consistent with a significant role in the composition of sebum [1].


  1. Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily. Turkish, A.R., Henneberry, A.L., Cromley, D., Padamsee, M., Oelkers, P., Bazzi, H., Christiano, A.M., Billheimer, J.T., Sturley, S.L. J. Biol. Chem. (2005) [Pubmed]
WikiGenes - Universities