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Gene Review

PRSS35  -  protease, serine, 35

Homo sapiens

Synonyms: C6orf158, Inactive serine protease 35, MGC46520, UNQ522/PRO1057, dJ223E3.1
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High impact information on PRSS35

  • Collectively, these results suggest that the PRSS35 and PRSS23 genes have been conserved as critical ovarian proteases throughout the course of vertebrate evolution [1].
  • PRSS35 possesses general features that are characteristic of serine (Ser) proteases, but is unique in that the canonical Ser that defines this enzyme family is replaced by a threonine (Thr) [1].


  1. The identification of novel ovarian proteases through the use of genomic and bioinformatic methodologies. Miyakoshi, K., Murphy, M.J., Yeoman, R.R., Mitra, S., Dubay, C.J., Hennebold, J.D. Biol. Reprod. (2006) [Pubmed]
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