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Chemical Compound Review

AmbotzHAA1166     (2S,3R)-2-amino-3-hydroxy- butanamide

Synonyms: AKOS006350428, AC1L9FO4, 49705-99-9, EINECS 256-437-4, (2S,3R)-2-amino-3-hydroxybutanamide, ...
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Disease relevance of threonine


Psychiatry related information on threonine


High impact information on threonine

  • This network involves receptor serine/threonine kinases at the cell surface and their substrates, the SMAD proteins, which move into the nucleus, where they activate target gene transcription in association with DNA-binding partners [11].
  • The 20S (700-kDa) proteasome contains multiple peptidase activities that function through a new type of proteolytic mechanism involving a threonine active site [12].
  • The protein serine/threonine phosphatase protein phosphatase-1 (PP1) is a ubiquitous eukaryotic enzyme that regulates a variety of cellular processes through the dephosphorylation of dozens of substrates [13].
  • Calcineurin is a eukaryotic Ca(2+)- and calmodulin-dependent serine/threonine protein phosphatase [14].
  • This review deals with the influence of serine/threonine-specific protein phosphatases on the function of ion channels in the plasma membrane of excitable tissues [15].

Chemical compound and disease context of threonine


Biological context of threonine


Anatomical context of threonine


Associations of threonine with other chemical compounds


Gene context of threonine


Analytical, diagnostic and therapeutic context of threonine


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