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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Bbox1  -  butyrobetaine (gamma), 2-oxoglutarate...

Mus musculus

Synonyms: AI874739, Gamma-BBH, Gamma-butyrobetaine dioxygenase, Gamma-butyrobetaine hydroxylase, Gamma-butyrobetaine,2-oxoglutarate dioxygenase
 
 
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High impact information on Bbox1

  • Among these inhibitors, the most potent was mildronate (3-(2,2,2-trimethylhydrazinium)propionate), known as a gamma-butyrobetaine hydroxylase inhibitor [1].
  • Hepatic gamma-butyrobetaine hydroxylase activity in rats and humans is developmentally regulated, and is increased by dietary L-thyroxine in adult rats [2].

References

  1. Carnitine transport into muscular cells. Inhibition of transport and cell growth by mildronate. Georges, B., Le Borgne, F., Galland, S., Isoir, M., Ecosse, D., Grand-Jean, F., Demarquoy, J. Biochem. Pharmacol. (2000) [Pubmed]
  2. Sites and regulation of carnitine biosynthesis in mammals. Rebouche, C.J. Fed. Proc. (1982) [Pubmed]
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