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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

adr-1  -  Protein ADR-1

Caenorhabditis elegans

 
 
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High impact information on adr-1

  • We find, however, that transgenes expressed in the somatic tissues of wild-type animals are silenced in strains with deletions in the two genes encoding ADARs, adr-1 and adr-2 [1].
  • We find that adr-1 is expressed in most, if not all, cells of the C.elegans nervous system and also in the developing vulva [2].
 

Other interactions of adr-1

  • We describe the two C.elegans ADAR genes, adr-1 and adr-2, and characterize strains containing homozygous deletions in each, or both, of these genes [2].

References

  1. The role of RNA editing by ADARs in RNAi. Knight, S.W., Bass, B.L. Mol. Cell (2002) [Pubmed]
  2. RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans. Tonkin, L.A., Saccomanno, L., Morse, D.P., Brodigan, T., Krause, M., Bass, B.L. EMBO J. (2002) [Pubmed]
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