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Gene Review

polh-1  -  Protein POLH-1

Caenorhabditis elegans

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High impact information on polh-1

  • Silencing requires rad-2, gei-17, and the polh-1 translesion DNA polymerase, which suppress replication fork stalling and thereby eliminate the checkpoint-activating signal [1].


  1. Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos. Holway, A.H., Kim, S.H., La Volpe, A., Michael, W.M. J. Cell Biol. (2006) [Pubmed]
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