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Gene Review

coq-8  -  Protein COQ-8

Caenorhabditis elegans

 
 
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High impact information on coq-8

  • In this paper we demonstrate that absence in ubiquinone in coq-1, coq-2 or coq-8 mutants lead to larval development arrest, slowed pharyngeal pumping, eventual paralysis and cell death [1].
  • To study coq-8 expression pattern, we have developed a C. elegans transgenic strain expressing ubiquinone biosynthesis coq-8 gene promoter and GFP construct [2].

References

  1. C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development. Gavilán, A., Asencio, C., Cabello, J., Rodríguez-Aguilera, J.C., Schnabel, R., Navas, P. Biofactors (2005) [Pubmed]
  2. Differential expression pattern of coq-8 gene during development in Caenorhabditis elegans. Asencio, C., Rodríguez-Aguilera, J.C., Vázquez, R., Baylis, H., Cabello, J., Schnabel, R., Gavilán, A., Navas, P. Gene Expr. Patterns (2006) [Pubmed]
 
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